Terpenoids as Cytotoxic Compounds: A Perspective
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- 1Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Uttar Pradesh, INDIA.
CORRESPONDENCE
Ved Prakash
Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Uttar Pradesh, INDIA.
Volume 12, Issue 24 · pp. 166-176 · 2018 · DOI: 10.4103/phrev.phrev_3_18
ABSTRACT
Natural products serve as safe and effective therapeutic agents for the drug discovery. Plants produce bioactive secondary metabolites such as terpenoids, alkaloids, tannins, saponins, and others, which have profusely been studied for anti‑infective, anticancer, anti‑inflammatory potential, and metabolic disorders to name a few. Terpenoids constitute the largest class of natural compound. The study investigates the novel cytotoxic compound of the terpenoid family isolated from different natural sources. The anticancerous activities of the compounds discussed in this review are taken from the published articles showing activity against specific cancer cell lines. The compounds exclusively belong to terpenoid family. Considering the huge potential of plant‑based natural products in drug discovery program and the contribution of terpenoid in the production of anticancer compounds, it can be exploited for more reliable economical and environmentally safe bioactive molecules.
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Prakash, V. (2018). Terpenoids as Cytotoxic Compounds: A Perspective. Pharmacognosy Reviews, 12(24), 166-176. https://doi.org/10.4103/phrev.phrev_3_18
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This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which allows others to share and adapt the work for any purpose, as long as the original authors and source are credited. CC BY 4.0