https://phcogrev-copy.vercel.app/ New articles published in Pharmacognosy Reviews. en Tue, 03 Nov 2026 00:00:00 GMT https://phcogrev-copy.vercel.app/article/21/41/1 https://phcogrev-copy.vercel.app/article/21/41/1 Tue, 03 Nov 2026 00:00:00 GMT Neha Badukale, Sanskruti Khalokar, Khushi Dubey, Rutuja Yawale, Abhiraj Gohatre, Piyush Hamand, Abhijit Raut, Harigopal Sawarkar Pharmacognosy Reviews ABSTRACT: Mimosa pudica Linn., belonging to Fabaceae family is well known by its unique seismonastic movement of leaves and a variety of therapeutic uses. The plant has a wide range of pharmacological effects, and it is traditionally used in many indigenous medicinal systems, which are anti-inflammatory, antioxidant, antimicrobial, antidiabetic, and wound-healing. Phytochemistry studies have shown the existence of alkaloids, flavonoids, tannins, and glycosides which are the major causes of its… https://phcogrev-copy.vercel.app/article/21/41/13 https://phcogrev-copy.vercel.app/article/21/41/13 Tue, 03 Nov 2026 00:00:00 GMT Manish Kumar, Shruti Thakur, Vishnu Das, Joohee Pradhan, Isha Sharma Pharmacognosy Reviews ABSTRACT: W. fruticosa categorized from family "Lythraceae" and it is also known as "Fire-flame bush" and it grow in tropical and subtropical regions. It occurs in Africa, Middle East and Asia. According to WHO reports that more than 80% of rural areas use medicinal plant to meet their healthcare needs. It plays vital role in ayurvedic medicine because they are used to make herbal medicine like arishta and asava. Researchers found that plant contains many natural phytochemicals such as tannins,… https://phcogrev-copy.vercel.app/article/21/41/21 https://phcogrev-copy.vercel.app/article/21/41/21 Tue, 03 Nov 2026 00:00:00 GMT Anshika Thakur, Shruti Thakur, Vishnu Das, Vandana Sharma, Arun Thakur Pharmacognosy Reviews ABSTRACT: Bergenia ciliata (Haw.) Sternb, is generally known as Pashanbheda, is a perennial medicinal herb commonly found in Himalayan region. Traditionally the plant has been used in the treatment of urolithiasis (kidney stones), urinary tract disorders, inflammation, cough, wound healing, fever, and various gastrointestinal disorders. Phytochemical investigation has identified various bioactive phytochemicals such as bergenin, gallic acid, catechin, tannins, arbutin, β-sitosterol, flavonoids,… https://phcogrev-copy.vercel.app/article/21/41/27 https://phcogrev-copy.vercel.app/article/21/41/27 Tue, 03 Nov 2026 00:00:00 GMT Arun Thakur, Shruti Thakur, Vishnu Das, Rahul Sharma, Anshika Thakur Pharmacognosy Reviews ABSTRACT: The genus Curcuma (family Zingiberaceae) contains more than 100 species which are mostly found in tropical and subtropical regions. Curcuma amada Roxb., is one of the most important species of Curcuma genus and it is commonly known as mango ginger due to its mango like fragrance and it has significant therapeutic potential. It has traditionally been used in Ayurveda, Unani and folk medicine system for its anti-inflammatory, wound healing and respiratory ailment potential. Curcuma… https://phcogrev-copy.vercel.app/article/21/41/33 https://phcogrev-copy.vercel.app/article/21/41/33 Tue, 03 Nov 2026 00:00:00 GMT Vishal Thakur, Vishnu Das, Shruti Thakur, Bharat Kumar, Muskan Singh Pharmacognosy Reviews ABSTRACT: B. monnieri, an herbal plant also referred to as brahmi, is an herb with medicinal and pharmacological active plant in traditional Indian medicinal history which has been broadly used in the an ancient ayurveda for improving memory, cognitive function, and neurological health. Brahmi is an ancient medicinal plant which used to prepare herbal formulations like brahmi ghritam, brahmi rasadi tailam, bacognize®, and bacomind®, which traditionally use in India for enhance memory and… https://phcogrev-copy.vercel.app/article/21/41/39 https://phcogrev-copy.vercel.app/article/21/41/39 Tue, 03 Nov 2026 00:00:00 GMT Isha Sharma, Visnu Das, Shruti Thakur, Harsh Kumar Chauhan, Manish Kumar Pharmacognosy Reviews ABSTRACT: Due to their broad range of therapeutic potential, low cost, and comparatively less side effects than manufactured medications, medicinal plants gained significant attention, among medicinal plant Pistacia integerrima has considered more attraction towards because it is rich in phytochemicals. Pistacia integerrima contain many phytochemical and secondary metabolites like flavonoids, alpha-pinene, sterols, terpenoids, kaempferol, catechins, fisetin, m-cymene, fenchyl alcohol, tannins,… https://phcogrev-copy.vercel.app/article/21/41/45 https://phcogrev-copy.vercel.app/article/21/41/45 Tue, 03 Nov 2026 00:00:00 GMT Riya Rajput, Sumitra Singh, Bhawna Parmar, Rakesh K Sindhu Pharmacognosy Reviews ABSTRACT: Pyracantha (Rosaceae family) is the name of evergreen shrub plants that are widely spread in Asia and Europe, and it is traditionally utilized in folk remedy to treat several diseases. Various species for example Pyracantha crenulata, Pyracantha fortuneana, Pyracantha coccinea, Pyracantha koidzumii and Pyracantha angustifolia possess nutritional and medicinal importance. The current review provides information about ethno medicinal uses, phytochemicals composition, and pharmacological… https://phcogrev-copy.vercel.app/article/21/41/71 https://phcogrev-copy.vercel.app/article/21/41/71 Tue, 03 Nov 2026 00:00:00 GMT Rehmat Jahan, Shoeb Ahmed Ansari, Asma Sattar Khan Pharmacognosy Reviews ABSTRACT: Artemisia absinthium L. (Wormwood), a medicinal herb of the family Asteraceae, has been extensively used in traditional systems of medicine, particularly the Unani system, for the management of a wide range of ailments. This review critically summarizes the botanical features, phytochemical profile, traditional applications, pharmacological activities, and safety aspects of A. absinthium based on classical Unani literature and contemporary scientific evidence. The plant contains a… https://phcogrev-copy.vercel.app/article/21/41/79 https://phcogrev-copy.vercel.app/article/21/41/79 Tue, 03 Nov 2026 00:00:00 GMT Anshita, Anshu Dalal, Gobind Yadav, Arun Nanda Pharmacognosy Reviews ABSTRACT: Plants have been recognized as a very useful and important source of drugs, since time immemorial. However, in the present day, context, usefulness of plants has been questioned, on the grounds of quality control, lack of clinical trials, etc. Historically, plant drugs listed in "Official books" under "Schedule I" of the Drugs and Cosmetics Act, 1940, were accepted for marketing in India, without any need for clinical trials. However, such drugs, although marketed in India, could not… https://phcogrev-copy.vercel.app/article/21/41/98 https://phcogrev-copy.vercel.app/article/21/41/98 Tue, 03 Nov 2026 00:00:00 GMT Adeeba Shaikh, Sachin Bhosale, Nirmala Shinde, Khushi Dolas, Devashree Bute Pharmacognosy Reviews ABSTRACT: Nutraceuticals combine nutritional benefits with biologically active components that may support health and help reduce the risk of certain health disorders, with plant proteins from legumes, cereals, pulses, soybean, and oilseeds providing an accessible and nutritious alternative to animal-derived proteins. This review aims to highlight the nutritional importance of plant proteins and their associated bioactive compounds, with an emphasis on their potential application in developing… https://phcogrev-copy.vercel.app/article/21/41/112 https://phcogrev-copy.vercel.app/article/21/41/112 Tue, 03 Nov 2026 00:00:00 GMT Mohsen Akbaribazm Pharmacognosy Reviews ABSTRACT: Brain tumours, particularly Glioblastoma (GBM), remain among the most aggressive malignancies because of profound molecular heterogeneity, Blood-Brain Barrier (BBB)-restricted drug delivery, therapeutic resistance, and an immunosuppressive tumour microenvironment. Naturally occurring dietary isoflavonoids, including genistein, daidzein, biochanin A, formononetin, glycitein, and the metabolite equol, have emerged as promising multitarget phytochemicals with potential applications in… https://phcogrev-copy.vercel.app/article/21/41/133 https://phcogrev-copy.vercel.app/article/21/41/133 Tue, 03 Nov 2026 00:00:00 GMT Rima Mohamad Kheir El Boukhary, Zeina Omeiche, Ali Wassef Assi, Abdel Rahman Ibrahim, Adam Wael Jundi, Assia Fadi Hachichou, Fathalla Mosaad Negm, Judy Khaled Radwan, Mohammad Ghalayini, Yara Al Zohbi, Zeinab Fawaz, Mohamad Ali Hijazi, Abdalla El-Lakany, Maha Aboul Ela Pharmacognosy Reviews ABSTRACT: Genus Xanthium (Asteraceae family) consists of 25 species that are distributed worldwide. Among these, only a few species, such as Xanthium strumarium and Xanthium spinosum have been extensively investigated for their pharmacological and phytochemical properties. These studies have revealed various activities, including analgesic, anti-inflammatory, anti-arthritic, cytotoxic, anti-angiogenic, and antiviral effects. This review covers most of the identified chemical constituents of… https://phcogrev-copy.vercel.app/article/21/41/141 https://phcogrev-copy.vercel.app/article/21/41/141 Tue, 03 Nov 2026 00:00:00 GMT Sanjib Kumar Panda, Nilima Mohanty, Pallavi Khuntia, Aakankhika Ray, Soumya Subhashree Satapathy, Ashwini Mallad, Deepak Jena Pharmacognosy Reviews ABSTRACT: Brassica sp., including kale, cabbage, broccoli, and cauliflower, contains bioactive compounds like flavonoids and phenolic acids, which make them nutritionally and therapeutically valuable. This study aimed to detect polyphenolic compounds in selected Brassica sp. (kale, cabbage, broccoli, and cauliflower) and to optimize a mobile phase to obtain better separation of these polyphenolic compounds using High-Performance Thin-Layer Chromatography (HPTLC). Standards including rutin,… https://phcogrev-copy.vercel.app/article/21/41/150 https://phcogrev-copy.vercel.app/article/21/41/150 Tue, 03 Nov 2026 00:00:00 GMT Mueen Ahmed KK Pharmacognosy Reviews Dear Editor, outcomes-so the label “antioxidant” spans agents that harm, agents that do nothing, and agents that help, depending on the endpoint. Reviews and meta-analyses frequently pool diverse compounds under the single heading of “antioxidants,” as if membership in that category predicted a common biological effect. I write to argue, using selenium as a case in point, that this lumping obscures more than it reveals. Selenium illustrates the point sharply. According to PubMed, although the… https://phcogrev-copy.vercel.app/article/20/40/102 https://phcogrev-copy.vercel.app/article/20/40/102 Mon, 03 Aug 2026 00:00:00 GMT Harsh J. Pathrabe, Snehal P. Shingade, Rajendra B. Kakde Pharmacognosy Reviews Calendula officinalis (CO) Linn. is a renowned medicinal herb belonging to the Asteraceae family. within the plant kingdom. Various online bibliographic data bases namely, Google scholar, PubMed, Scifinder, and Web of Science were used for integrating information. This plant comprises alkaloid glycosides, saponins, flavonoids, carotenoids, triterpenoids, oils, amino acids, steroids, and quinones. These chemical compounds exhibit diverse pharmacological effects including anti-inflammatory,… https://phcogrev-copy.vercel.app/article/20/40/110 https://phcogrev-copy.vercel.app/article/20/40/110 Mon, 03 Aug 2026 00:00:00 GMT Abdullah Faisal Albukhari Pharmacognosy Reviews Neuropsychiatric and neurodegenerative conditions are widespread across the globe, frequently linked to disturbances in monoaminergic transmission, increased cortical excitability, and maladaptive responses to stress. Existing pharmacological treatments are often hindered by delayed onset of action, limited effectiveness, and adverse side effects. This narrative review provides a critical examination of the neurochemical and electrophysiological characteristics of Peganum harmala L. (Syrian… https://phcogrev-copy.vercel.app/article/20/40/123 https://phcogrev-copy.vercel.app/article/20/40/123 Mon, 03 Aug 2026 00:00:00 GMT Barkha Tirpude, Bharat Rathi Pharmacognosy Reviews Zingiber officinale Roscoe's ginger is a widely used and ubiquitous spice. Among its many chemical components are phenolic chemicals, terpenes, polysaccharides, lipids, organic acids, and unprocessed fibers. The health benefits of ginger are mainly attributed to phenolic components like gingerols and shogaols. It has been utilized for several biological purposes in Ayurvedic medicine from ancient times. The objective of this systematic review is to evaluate and compile the available data… https://phcogrev-copy.vercel.app/article/20/40/131 https://phcogrev-copy.vercel.app/article/20/40/131 Mon, 03 Aug 2026 00:00:00 GMT Mayuri Padghan, Aishwarya Jogi, Shrutika Ghurde, Anushka Mandale, Gayatri Wankhade, Nikita Kaware, Neha A. Badukale, Abhijit S. Raut, Harigopal S. Sawarkar Pharmacognosy Reviews The traditional medicinal herb Aegle marmelos (L.) Correa, also referred to as bilva or bael, has a long history in India's Ayurvedic system. Ancient writings such as the Charka Samhita and the Vedas describe its medicinal applications. The substantial study on its phytochemistry, pharmacological characteristics, and therapeutic potential is compiled in this review. Bioactive chemicals are abundant in the plant's leaves, bark, fruits, and roots, among other sections. More than 100 different… https://phcogrev-copy.vercel.app/article/20/40/141 https://phcogrev-copy.vercel.app/article/20/40/141 Mon, 03 Aug 2026 00:00:00 GMT Mueen Ahmed KK, Mohammed Yunus Pharmacognosy Reviews Neurodegenerative Disorders (NDDs), including Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Amyotrophic Lateral Sclerosis (ALS), Huntington’s Disease (HD), and Multiple Sclerosis (MS) represent a growing global health burden, affecting hundreds of millions of individuals worldwide. A central mechanistic driver of neurodegeneration is oxidative stress, defined as an imbalance between Reactive Oxygen Species (ROS) generation and endogenous antioxidant defense systems. Natural products… https://phcogrev-copy.vercel.app/article/20/40/154 https://phcogrev-copy.vercel.app/article/20/40/154 Mon, 03 Aug 2026 00:00:00 GMT Richa Mehta, Salini Nair, Sahyadri Manjunath, Santhepete Nanjundaiah Manjula, Gokul Ramesh, Sathish Kumar Gunasekaran, Mamatha Gavisiddaiah, Prashant Yuvaraj Mali Pharmacognosy Reviews Parkinson's Disease (PD) is a progressive neurodegenerative disease characterized by the degeneration of dopaminergic neurons in the substantia nigra, which results in motor control problems. One of the main pathological aspects is the presence of alpha-synuclein aggregates, which are called Lewy bodies. Neuroinflammation is at the centre of PD progression and the contribution of activated microglia, lymphocyte invasion, and increased pro-inflammatory cytokines to neuronal damage.… https://phcogrev-copy.vercel.app/article/20/40/170 https://phcogrev-copy.vercel.app/article/20/40/170 Mon, 03 Aug 2026 00:00:00 GMT Rajeshwari Anand Wankhade, Shweta Saboo Pharmacognosy Reviews Oral ulcers are painful inflammatory lesions of the oral mucosa that interfere with eating, speaking, swallowing, and overall quality of life. Recurrent aphthous stomatitis, traumatic ulcers, chemically induced ulcers, and inflammatory mucosal lesions are commonly encountered forms. Although topical corticosteroids, antiseptics, local anesthetics, protective gels, and herbal preparations are widely used, their therapeutic action is frequently limited by rapid salivary washout, short mucosal… https://phcogrev-copy.vercel.app/article/20/40/178 https://phcogrev-copy.vercel.app/article/20/40/178 Mon, 03 Aug 2026 00:00:00 GMT Mueen Ahmed KK Pharmacognosy Reviews Debate over whether athletes should take antioxidant supplements often proceeds as though a single answer must apply at all times. I write to suggest that the more useful question is not whether, but when—and that antioxidant advice should be periodized to the training phase. According to PubMed, antioxidant supplementation can blunt the redox-sensitive signaling—through pathways such as MAPK and PGC-1α—that drives mitochondrial biogenesis and other adaptations to training, which argues against… https://phcogrev-copy.vercel.app/article/20/39/1 https://phcogrev-copy.vercel.app/article/20/39/1 Wed, 11 Mar 2026 00:00:00 GMT Mohan Parameswari, Karunamoorthy Jayamoorthy, S. Savitha Pharmacognosy Reviews India's vast biodiversity includes a myriad of medicinal plants that have been utilized in traditional medicine for millennia. Plants have been integral to human health and medicine since ancient times, offering a vast array of pharmacologically active compounds with diverse therapeutic potentials. This review explores the broad spectrum of pharmacological properties exhibited by plants, encompassing antioxidant, antimicrobial, anti-inflammatory, anticancer, and other bioactive activities.… https://phcogrev-copy.vercel.app/article/20/39/25 https://phcogrev-copy.vercel.app/article/20/39/25 Wed, 11 Mar 2026 00:00:00 GMT Shweta Saboo, Shraddha Sapkal, Vaishanavi Nimbalkar Pharmacognosy Reviews The greatest class of plant-derived polyphenolic chemicals are called flavonoids; they have a wide range of biological effects in both in vitro and in vivo mammalian cell systems. Rutin is one of more prominent flavonoid possessing wound healing, anti-inflammatory, antimicrobial, anti-mutagenic, anti-oxidant, and anti-HIV (Human Immunodeficiency Virus) property. The modification of Rutin’s structure aims to enhance the bioavailability, potency and target specificity. The exploration of… https://phcogrev-copy.vercel.app/article/20/39/34 https://phcogrev-copy.vercel.app/article/20/39/34 Wed, 11 Mar 2026 00:00:00 GMT Surendra Jugguru, Raju Chatakondu, Shobha Singarapalle, Praveena Thirunalveli Pharmacognosy Reviews Numerous fungal endophytes produce plant-derived chemicals that are pharmacologically useful, making them well-known sources of naturally occurring, biologically active compounds. Alkaloids, coumarins, flavonoids, glycosides, lignans, phenylpropanoids, quinones, saponins, terpenoids, and xanthones, all produced by endophytic fungi, are common plant-derived therapeutic chemicals included in this study. This overview covers research from the initial discovery of Taxol production by endophytic… https://phcogrev-copy.vercel.app/article/20/39/41 https://phcogrev-copy.vercel.app/article/20/39/41 Wed, 11 Mar 2026 00:00:00 GMT V.S. Thiruvengadarajan, A. Rajasekaran, A. Manimegalai, V. Lal Muthukumar, P. Mathialagan, V.S. Santhosh, T. Thamayanthi Pharmacognosy Reviews Wound healing and inflammation are highly intricate biological processes that work to restore the body’s tissue structure and function after injury. In recent years, growing interest has focused on plant-based bioactive compounds as promising therapeutic options, largely because of their proven effectiveness, safety, and low risk of side effects. A wide range of phytochemicals-such as flavonoids, alkaloids, tannins, saponins, terpenoids, and phenolic compounds-have shown strong wound-healing… https://phcogrev-copy.vercel.app/article/20/39/48 https://phcogrev-copy.vercel.app/article/20/39/48 Wed, 11 Mar 2026 00:00:00 GMT Heena Sachdeva, Manish Sharma, Maninder M Pharmacognosy Reviews The global outbreak of Coronavirus Disease 2019 (COVID-19), caused by SARS-CoV-2, has presented significant challenges to healthcare systems. Despite the availability of vaccines and antiviral agents, the evolving nature of viral variants necessitates the exploration of complementary strategies. Immunomodulation, particularly through plant-based agents, has emerged as a promising adjunctive approach to manage COVID-19 by restoring immune balance and attenuating hyperinflammation. This review… https://phcogrev-copy.vercel.app/article/20/39/54 https://phcogrev-copy.vercel.app/article/20/39/54 Wed, 11 Mar 2026 00:00:00 GMT Siddhant Krishna, Sandip Chatterjee, Pawan Kumar Goswami Pharmacognosy Reviews Green tea is rich in catechins, which are polyphenolic chemicals that have strong anticancer effects through pro-apoptotic, anti-inflammatory, and antioxidant processes. They alter a number of molecular pathways, including as those that control the course of the cell cycle, limit angiogenesis, and reduce metastasis. With traditional Chemotherapeutics, Epigallocatechin Gallate (EGCG), the most researched catechin, exhibits synergistic actions that increase efficacy and decrease toxicity.… https://phcogrev-copy.vercel.app/article/20/39/63 https://phcogrev-copy.vercel.app/article/20/39/63 Wed, 11 Mar 2026 00:00:00 GMT Saurav Talukdar, Suman Kumar, Sarbanga Bezbaruah, Prerana Kashyap, Mohsin Ahmed, Rupjyoti Majumder, Rajsekhar Das, N. Anirudh Singh Pharmacognosy Reviews Hymenocallis littoralis (Jacq.) Salisb., commonly known as the Beach spider lily is a perennial herbaceous plant that belongs to the family Amaryllidaceae; well known for its distinctive ethnomedicinal uses against different serious ailments. The review critically analysed the distribution, traditional uses, phytoconstituents, and pharmacological activity of the plant H. littoralis. All the information described in this study was collected by using the electronic databases comprising PubMed and… https://phcogrev-copy.vercel.app/article/20/39/79 https://phcogrev-copy.vercel.app/article/20/39/79 Wed, 11 Mar 2026 00:00:00 GMT Roshan Manger, Jun Moni Kalita, Sonam Bhutia Pharmacognosy Reviews The Manger community, one of the indigenous communities living in Sikkim's Gangtok district since ages, has ethnomedical practices that are examined and documented in this study. Important information on 40 medicinal plant species used to cure a variety of illnesses was gathered through field surveys and interviews with five identified traditional healers. Quantitative analysis was employed using the Informant Consensus Factor (ICF) and Use Value (UV). These plants-mostly herbs (70%)-are used…