Pharmacognosy Reviews logo
Review

Pharmacological and Therapeutic Potential of Neem (Azadirachta indica)

1, 1, 1, 1

  1. 1Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, SAUDI ARABIA.

CORRESPONDENCE

Arshad Husain Rahmani

Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah, SAUDI ARABIA.

ah.rahmani@qu.edu.sa

Volume 12, Issue 24 · pp. 250-255 · 2018 · DOI: 10.4103/phrev.phrev_8_18

ABSTRACT

Azadirachta indica, a member of the Meliaceae family, is commonly known as neem and its role in disease cure has been documented. Different parts of this tree contain numerous types of ingredients such as azadirachtin and quercetin and limonoids such as nimbin, nimbidin, and nimbinin with diverse pharmacological activities. Neem tree parts have also been used as a general folk medicine, and more recently, its constituents have been purified and found to possess greater antioxidant, hepatoprotective, antimicrobial, and anticancerous activities. Moreover, its constituents also show therapeutic implications in the modulation of cell signaling pathways involved in the management of cancer. Moreover, neem and its ingredient might be a potential candidate in prevention and treatment of tumor due to its broader pharmacological activities. This review presents an overview of the health‑promoting effects of neem and its ingredients through modulation of biological activities.

KEYWORDS

Open in new tab

REFERENCES

As published

Showing references and in-text citations exactly as published.

    Cite this article

    SELECT FORMAT

    Rahmani, A. H., Almatroudi, A., Alrumaihi, F., & Khan, A. A. (2018). Pharmacological and Therapeutic Potential of Neem (Azadirachta indica). Pharmacognosy Reviews, 12(24), 250-255. https://doi.org/10.4103/phrev.phrev_8_18

    Copyright and licence

    © 2018 Author(s)

    This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 License, which allows others to share and adapt the work for any purpose, as long as the original authors and source are credited. CC BY 4.0